id author title date pages extension mime words sentences flesch summary cache txt cord-295850-nb6miso7 Zhang, Chuan-hai Immune responses in Balb/c mice induced by a candidate SARS-CoV inactivated vaccine prepared from F69 strain 2005-05-02 .txt text/plain 2930 161 55 title: Immune responses in Balb/c mice induced by a candidate SARS-CoV inactivated vaccine prepared from F69 strain The immunogenicity of a candidate-inactivated vaccine prepared from SARS-CoV F69 strain was evaluated in Balb/c mice. The present study was performed with the objective of determining the immunogenicity of a candidate-inactivated SARS-CoV vaccine made from F69 strain in Balb/c mice. In test groups, anti-SARS-CoV specific IgM antibodies were induced by the inactivated vaccine. The results showed that SARS-CoV F69 strain inactivated vaccine could induce potent humoral immune responses in Balb/c mice. In present study, the specificity of serum antibodies induced by F69 strain inactivated vaccine was identified by Western blot assay. A convalescent serum of SARS patient was used, and the same positive result was obtained (lane 3, Fig. 4) , which further demonstrated the specificity of the antibodies induced with the inactivated vaccine produced from F69 strain. ./cache/cord-295850-nb6miso7.txt ./txt/cord-295850-nb6miso7.txt