id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-295846-quhnesbr	Li, Huan	Impact of corticosteroid therapy on outcomes of persons with SARS-CoV-2, SARS-CoV, or MERS-CoV infection: a systematic review and meta-analysis	2020-05-05		.txt	text/plain	2788	185	45	In conclusion, corticosteroid use in subjects with SARS-CoV-2, SARS-CoV, and MERS-CoV infections delayed virus clearing and did not convincingly improve survival, reduce hospitalization duration or ICU admission rate and/or use of mechanical ventilation. Because of the overlapping genetic and clinical feature of SARS-CoV-2, SARS-CoV, and MERS-CoV, we performed a meta-analysis of safety and efficacy of corticosteroid use in these coronavirus infections. Our meta-analysis focus on the effects of corticosteroids on virus clearing and mortality in persons infected with SARS-CoV-2, SARS-CoV, or MERS-CoV. Inclusion criteria included: (1) research articles including observational studies and clinical trials but excluding reviews or case reports on the use of corticosteroids in persons with SARS-CoV-2, SARS-CoV, and MERS-CoV infections; (2) reported outcomes of virus clearance and/or death; and (3) published in English and/or Chinese. To test impact of corticosteroid use on duration of hospitalization we included 3 studies [12, 13, 16] involving 828 subjects (SARS, N = 519; MERS, N = 309).	./cache/cord-295846-quhnesbr.txt	./txt/cord-295846-quhnesbr.txt