id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-294931-a77g9rjo	Zhang, Linqi	Antibody responses against SARS coronavirus are correlated with disease outcome of infected individuals	2005-11-18		.txt	text/plain	4013	193	52	While there is no systematic evaluation of cytotoxic T-cell (CTL) activity in infected patients, there are some reports showing detection of binding antibodies to nucleocapsid (N) and spike (S) glycoprotein after about 2 weeks, remaining detectable for as long as 210 days after the onset of symptoms [Shi et al., 2003 Huang et al., 2004; Leung et al., 2004; Liu et al., 2004; Nie et al., 2004a; Temperton et al., 2005] . In this report, using both the ELISA-based and pseudotyped retrovirus-based neutralization systems, we characterized temporal changes in N protein-specific antibody and S glycoprotein-specific Nab responses in infected patients who have either recovered from or succumb to SARS-CoV infection. Since the 293/ACE2 cell line is the most susceptible to entry of the pseudotyped retrovirus bearing S glycoprotein, we chose this cell line for studies of neutralization antibody (Nab) activities of serum samples collected from SARS-CoV-infected patients.	./cache/cord-294931-a77g9rjo.txt	./txt/cord-294931-a77g9rjo.txt