id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-294441-nehorqhi	O’Brien, Stephen J.	Plagues and adaptation: Lessons from the Felidae models for SARS and AIDS	2006-08-31		.txt	text/plain	6767	390	50	A highly virulent feline coronavirus epidemic in African cheetahs, a disease model for human SARS, illustrates the critical role of ancestral population genetic variation. As these examples illustrate, strong parallels exist between disease in human and endangered wildlife and argue for an integration of the research fields of comparative genomics, infectious disease, epidemiology, molecular genetics and population biology for an effective proactive conservation approach. Representing carnivores, the cat family Felidae offers numerous examples of reduced genetic var-iation in natural populations common to endangered species including Asian lion (Panthera leo persica) (Gilbert et al., 1991) , cheetah (Acinonyx jubatus) (Menotti-Raymond and O'Brien, 1993) , tiger (P. Our ongoing research into host-pathogen interactions in the cat family Felidae offers additional insights on how the application of molecular genomic technologies to non-human animal species not traditionally studied in research laboratories holds real promise in conservation.	./cache/cord-294441-nehorqhi.txt	./txt/cord-294441-nehorqhi.txt