id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-294363-bv6xa8v8	Zhou, Hong	Potential Therapeutic Targets and Promising Drugs for Combating SARS‐CoV‐2	2020-05-05		.txt	text/plain	8902	456	46	Several studies demonstrated angiotensin converting enzyme 2 (ACE2) as an important therapeutic target of SARS-CoV-2 entry and infection, and many potential targets were subsequently proposed, such as the spike (S) protein and transmembrane serine protease 2 (TMPRSS2). Therefore, accelerating research for potential therapeutic target confirmation, promising drug discovery, and clinical verification development will speed up efforts to combat SARS-CoV-2. In addition to inhibiting the virus directly, ASOs are also expected to target the disease-related proteins involved in the inflammatory cytokine storm process, which could be considered a promising therapeutic strategy for combating SARS-CoV-2 . Although many strategies have been used to block the attachment, entry, replication and release processes to inhibit SARS-CoV-2 infection, how to prevent viral evasion from host immune responses and virus-induced cytopathic effects is considered one of the most urgent problems that need to be solved in SARS-CoV-2-induced pneumonia-associated respiratory syndrome (PARS) patients.	./cache/cord-294363-bv6xa8v8.txt	./txt/cord-294363-bv6xa8v8.txt