id author title date pages extension mime words sentences flesch summary cache txt cord-293543-87ulnpdm Shalhoub, Sarah Interferon beta-1b for COVID-19 2020-05-10 .txt text/plain 957 57 53 8 In The Lancet, Ivan Fan-Ngai Hung and colleagues 9 present the results of an open-label, randomised, phase 2 trial that examined the effect of a triple combination regimen of interferon beta-1b 8 million international units (0ยท25 mg) on alternate days, lopinavir 400 mg plus ritonavir 100 mg every 12 h, and ribavirin 400 mg every 12 h, compared with lopinavir 400 mg plus ritonavir 100 mg every 12 h alone. However, as the authors acknowledge, future studies to examine the efficacy of interferon beta-1b alone or in combination with other drugs to treat severe or critically ill patients with confirmed COVID-19 compared with placebo are warranted. Ribavirin and interferon alfa-2a for severe Middle East respiratory syndrome coronavirus infection: a retrospective cohort study Triple combination of interferon beta-1b, lopinavir-ritonavir, and ribavirin in the treatment of patients admitted to hospital with COVID-19: an open-label, randomised, phase 2 trial ./cache/cord-293543-87ulnpdm.txt ./txt/cord-293543-87ulnpdm.txt