id author title date pages extension mime words sentences flesch summary cache txt cord-292561-iy06b9h9 Miesbach, Wolfgang COVID-19: Coagulopathy, Risk of Thrombosis, and the Rationale for Anticoagulation 2020-07-17 .txt text/plain 4889 262 45 The novel coronavirus infection (COVID-19) is caused by the new coronavirus SARS-CoV-2 and is characterized by an exaggerated inflammatory response that can lead to severe manifestations such as adult respiratory syndrome, sepsis, coagulopathy, and death in a proportion of patients. 5 While most patients show only mild symptoms, 6 a characteristic feature of COVID-19 is that a proportion of patients develop severe complications within a short time after infection, such as adult respiratory syndrome (ARDS) or disseminated intravascular coagulation (DIC), sepsis followed by organ failure, and death. 15 These laboratory changes are consistent with previous studies which showed that hypoalbuminemia, lymphopenia, and C-reactive protein 4 mg/dL were the predictive factors for the progression of pneumonia to respiratory failure in MERS-CoV-infected patients and that elevated lactate dehydrogenase (LDH) levels were associated with hospital-acquired infection with SARS-CoV. ./cache/cord-292561-iy06b9h9.txt ./txt/cord-292561-iy06b9h9.txt