id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-289134-ne3tjt5g	Xing, Yue	Natural Polymorphisms Are Present in the Furin Cleavage Site of the SARS-CoV-2 Spike Glycoprotein	2020-07-17		.txt	text/plain	1628	93	58	By analyzing 45828 SARS-CoV-2 genome sequences, we identified 103 strains of SARS-CoV-2 with various DNA mutations including 18 unique non-synonymous point mutations, one deletion, and six gains of premature stop codon that may affect the furin cleavage site. From 45828 SARS-CoV-2 genome sequences available in the GISAID database as of June 13, 2020, 103 strains of SARS-CoV-2 1 https://www.ncbi.nlm.nih.gov/Class/Structure/aa/aa_explorer.cgi carried various DNA mutations including 25 unique ones that may affect the furin cleavage site located at the amino acid residual positions 680-689 (S1/S2 region) (Coutard et al., 2020; Wang et al., 2020; Zhang et al., 2020) of the SARS-CoV-2 spike protein (Figure 1 , Table 1, and Supplementary Table 1) . We uncovered 103 SARS-CoV-2 strains from multiple geographic regions, 81 of which carried 25 unique mutations that may affect the furin cleavage site in the spike glycoprotein.	./cache/cord-289134-ne3tjt5g.txt	./txt/cord-289134-ne3tjt5g.txt