id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-288756-r96izsyq	Wu, Zhiqiang	ORF8-Related Genetic Evidence for Chinese Horseshoe Bats as the Source of Human Severe Acute Respiratory Syndrome Coronavirus	2016-02-15		.txt	text/plain	2253	108	55	title: ORF8-Related Genetic Evidence for Chinese Horseshoe Bats as the Source of Human Severe Acute Respiratory Syndrome Coronavirus Several lineage B betacoronaviruses termed severe acute respiratory syndrome (SARS)–like CoVs (SL-CoVs) were identified from Rhinolophus bats in China. The nucleotide sequences in the ORF1ab, E, M, and N genes in these bat-borne lineage B beta-CoVs are 89%-93% similar to those in the SARS-CoVs from humans. Furthermore, genetic evidence for the identical ORF8 is needed to trace the origin of SARS-CoVs to bat SL-CoVs. All genome sequences were submitted to GenBank. In this study, a systematic survey of bat-borne CoVs was performed using bat virome data from throughout China, described in our previous report [6] , to obtain genetic evidence indicating the source of SARS-CoVs. Fifteen SL-CoVs were identified from 9 bat species in 11 provinces ( Figure 1A ) [6] . sinicus have nearly identical ORF8s and similar backbone genes to those in SARS-CoVs in Yunnan and Guangxi provinces.	./cache/cord-288756-r96izsyq.txt	./txt/cord-288756-r96izsyq.txt