id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-288153-2qsh2dlk	Hays, Priya	Clinical sequelae of the novel coronavirus: does COVID-19 infection predispose patients to cancer?	2020-05-27		.txt	text/plain	4322	225	41	Major signaling pathways implicated in aberrant cellular growth are activated, the ensuing cytokine storm weakens the immune system response to tumors, and patients may develop cancer as a result of superimposed mutagenic and/or carcinogenic events. There may be a distinct association between novel coronavirus infection and the onset of cancer through the activation of the MAPK and JAK-STAT signaling pathways and the NF-κB transcription factor. The turning on of oncogenic signaling pathways and the acute inflammatory response that results upon coronavirus infection can be hypothesized as being cancer inducing, or leading to the risk of developing cancer, especially if the patient has a superimposed mutagenic or carcinogenic event occurring concomitantly, even if the virus does not cause a chronic infection like viruses such as HCV, HCV and EBV. Oncologic sequelae of the novel coronavirus • Viral infection induces a robust immune response, a 'cytokine storm' leading to tissue damage and inflammation, which may predispose to cancer.	./cache/cord-288153-2qsh2dlk.txt	./txt/cord-288153-2qsh2dlk.txt