id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-285896-lb8toc1m	Beurton, Alexandra	Limiting positive end-expiratory pressure to protect renal function in SARS-CoV-2 critically ill patients	2020-07-10		.txt	text/plain	1013	66	55	Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) related pneumonia is a risk factor for acute respiratory distress syndrome (ARDS) and acute kidney injury (AKI) [1, 2] . Herein, we report our experience in SARS-CoV-2 critically ill patients before and after having modified our practices in the view of the high occurrence of AKI that needed renal replacement therapy (RRT) in the first cases we managed. During "period 1" (between 04 and 15 March 2020), all mechanically ventilated patients with confirmed SARS-CoV-2 admitted to our intensive care unit received volume-controlled ventilation with a tidal volume of 6 ml/kg of ideal body weight and PEEP stepwise increased to reach a plateau pressure below 28 cmH 2 O. Our findings suggest that changing our practices was associated with a decreased need for RRT and a lower proportion of patients with AKI KDIGO 3.	./cache/cord-285896-lb8toc1m.txt	./txt/cord-285896-lb8toc1m.txt