id author title date pages extension mime words sentences flesch summary cache txt cord-283486-ji0e8yoo Radulesco, Thomas Safety and Impact of Nasal Lavages During Viral Infections Such as SARS-CoV-2 2020-08-27 .txt text/plain 1600 122 46 8 Regarding severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), Carrouel et al found the use of a mouth rinses with local nasal applications that contain b-cyclodextrins combined with flavonoids agents reduce the viral load of saliva and nasopharyngeal microbiota, including potential SARS-CoV-2 carriage. Nasal mucosa have high viral loads and include cells expressing proteases responsible for virus entry (such as angiotensinconverting enzyme 2 and TMPRSS2 for SARS-CoV-2), 19, 20 The upper airway has shown to be a reservoir for descending bacterial or viral infection to the lung. 3, 23, 24 Given the potential benefits summarized above, nasal saline irrigation may enhance recovery in patients known to be infected with COVID-19. 26 The potential direct antiviral actions and reduction in viral load have led to proposals that use in patients with COVID-19 may reduce risk of nosocomial transmission. Copper enhanced nasal saline irrigations: a safe potential treatment and protective factor for COVID-19 infection? ./cache/cord-283486-ji0e8yoo.txt ./txt/cord-283486-ji0e8yoo.txt