id author title date pages extension mime words sentences flesch summary cache txt cord-282990-qb4wk4yb Chen, Zhuo Safety considerations in the bioanalytical laboratories handling specimens from coronavirus disease 2019 patients 2020-08-21 .txt text/plain 1971 113 48 Since blood specimen is one of the most commonly analyzed sample types, viral load of SARS-CoV-2 in blood is a key issue for laboratory biosafety. Besides the above three studies, other recently published papers also demonstrated that the detection rates of SARS-CoV-2 RNA in blood from COVID-19 patients were generally low as: five of 48 (10%) [1] , two of 9 (22%) [2] and six of 41 (15%) [3] . Despite the relatively low SARS-CoV-2 viral load detected in the blood and urine of COVID-19 patients, scientists have yet to draw conclusions about the infectivity of these specimens. The Centers for Disease Control and Prevention (CDC) has issued the interim laboratory biosafety guidelines for handling COVID-19 specimens, which recommends virus inactivation prior to sample processing to reduce the risk of infection [10] . Nevertheless, only the protocol of heating at 92 • C for 15 min completely inactivated SARS-CoV-2 in respiratory specimens with much higher viral load. ./cache/cord-282990-qb4wk4yb.txt ./txt/cord-282990-qb4wk4yb.txt