id author title date pages extension mime words sentences flesch summary cache txt cord-282862-kve6fa49 Pastick, Katelyn A A Systematic Review of Treatment and Outcomes of Pregnant Women with COVID-19 – A Call for Clinical Trials 2020-08-13 .txt text/plain 3313 206 47 Clinicaltrials.gov was searched for relevant studies, using the preprogrammed search terms "COVID-19," "SARS-CoV-2," "2019-nCoV," "2019 novel coronavirus," and "severe acute respiratory syndrome coronavirus 2." Inclusion and exclusion criteria were examined to determine whether pregnant and/or breastfeeding patients were excluded from the study. Of the actively ongoing interventional clinical trials investigating the use of a drug (including dietary supplements and biologic agents) that did not report the exclusion of pregnant or breastfeeding women, the first author contacted study personnel for each of these studies by email to discern whether or not pregnant or breastfeeding women were eligible to be enrolled. Despite available safety data in pregnancy for hydroxychloroquine and lopinavir/ritonavir, we were surprised to find 68% and 80% of the respective clinical trials had excluded pregnant or breastfeeding persons. Our review of the literature was timely and is the first study (to our knowledge) to systematically examine and compile the available data related to treatment and outcomes of COVID-19 in pregnancy and related clinical trials. ./cache/cord-282862-kve6fa49.txt ./txt/cord-282862-kve6fa49.txt