id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-282317-k9mtf6yl	Srivastava, Vivek	Molecular Docking and ADMET Study of Bioactive Compounds of Glycyrrhiza glabra Against Main Protease of SARS-CoV2	2020-10-14		.txt	text/plain	3964	190	51	The main objective of the present study is to carry out molecular docking analysis of Glycyrrhiza glabra active compounds, Glycyrrhizic acid, Liquiritigenin and Glabridin against the main protease (M pro ) one by one followed by molecular interaction study (hydrogen bond prediction between target and drugs), drug-likeness behaviour and ADMET prediction to confirm the efficiency and efficacy of these active compound against SARS-CoV2. The molecular docked pose of the minimum binding affinity conformer of the Gg active compounds that is glycyrrhizic acid, Glabridin and Liquiritigenin demonstrated that they also firmly goes and bind to the active site of the M pro protein of the SARS-CoV-2 ( figure 4 and table 2 ). Molecular docking indicated that the three active compounds of Glycyrrhiza glabra namely glycyrrhizic acid, Liquiritigenin, and Glabridin successfully docked with the amino acid molecule at the catalytic site of the M pro with a high negative binding affinity and formed several molecular interaction with the main protease of SARS-CoV2.	./cache/cord-282317-k9mtf6yl.txt	./txt/cord-282317-k9mtf6yl.txt