id author title date pages extension mime words sentences flesch summary cache txt cord-281508-zl2url8z Pearce, N. Is death from Covid-19 a multistep process? 2020-06-03 .txt text/plain 4997 245 53 The Covid-19 death rate increases exponentially with age, and the main risk factors are age itself, as well as having underlying conditions such as hypertension, diabetes, cardiovascular disease, severe chronic respiratory disease and cancer. Thus, death from Covid-19 and SARS appears to follow a distinct age-pattern, consistent with a multistep model of disease that in the case of Covid-19 is probably defined by comorbidities and age producing immune-related susceptibility. SARS showed a similar log-log age-pattern to that of Covid-19, albeit with a lower slope (indicating a smaller number of steps); in contrast, seasonal and pandemic influenza showed quite different agepatterns. These findings are consistent with a multistep model of disease involving a six-step process that in the case of SARS-COV-2 is probably defined by comorbidities and age producing immune-related susceptibility. ./cache/cord-281508-zl2url8z.txt ./txt/cord-281508-zl2url8z.txt