id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-281501-ca9oxl7f	Khan, Shumayila	Neuropathogenesis of SARS-CoV-2 infection	2020-07-30		.txt	text/plain	3208	163	43	Emerging reports of encephalopathies and similar ailments with the detection of the virus in the CSF has elicited an urgent need for investigating the possibility of neuroinvasiveness of the virus, which cannot be ruled out given the expression of low levels of ACE2 receptors in the brain. One study from Japan which described the first case of COVID-19-associated encephalitis where the patient was admitted for convulsions accompanied by unconsciousness reported that although the patient tested negative for SARS-CoV-2 in a nasopharyngeal swab, the viral RNA was surprisingly detected in the CSF, and the patient MRI exhibited abnormalities of the medial temporal lobe and hippocampus (Moriguchi et al., 2020) . The preliminary reports which hint towards the involvement of the CNS imply an urgent need for more studies, and a systematic collection and preservation of CSF samples along with associated clinical data, at least in patients displaying extrapulmonary or neurological symptoms, to examine the neuronal aspect of COVID-19.	./cache/cord-281501-ca9oxl7f.txt	./txt/cord-281501-ca9oxl7f.txt