id author title date pages extension mime words sentences flesch summary cache txt cord-280996-anq680a1 Agarwal, Arnav High-flow nasal cannula for acute hypoxemic respiratory failure in patients with COVID-19: systematic reviews of effectiveness and its risks of aerosolization, dispersion, and infection transmission 2020-06-15 .txt text/plain 7117 383 42 title: High-flow nasal cannula for acute hypoxemic respiratory failure in patients with COVID-19: systematic reviews of effectiveness and its risks of aerosolization, dispersion, and infection transmission Review 1: we synthesized results from randomized-controlled trials (RCTs) comparing HFNC to conventional oxygen therapy (COT) in critically ill patients with acute hypoxemic respiratory failure. Conclusions High-flow nasal cannula may reduce the need for invasive ventilation and escalation of therapy compared with COT in COVID-19 patients with acute hypoxemic respiratory failure. Conclusions High-flow nasal cannula may reduce the need for invasive ventilation and escalation of therapy compared with COT in COVID-19 patients with acute hypoxemic respiratory failure. We conducted two rapid systematic reviews commissioned by the WHO to summarize the evidence for the efficacy, safety, and risk of aerosol generation and infection transmission during HFNC use among patients with acute hypoxemic respiratory failure due to COVID-19. ./cache/cord-280996-anq680a1.txt ./txt/cord-280996-anq680a1.txt