id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-280062-1qrav1d5	McClenaghan, Elliot	The global impact of SARS-CoV-2 in 181 people with cystic fibrosis	2020-11-04		.txt	text/plain	1707	95	62	Whilst outcomes in this large cohort are better than initially feared overall, possibly due to a protective effect of the relatively younger age of the CF population compared to other chronic conditions, SARS-CoV-2 is not a benign disease for all people in this patient group. The characteristics of the 149 people in the non-transplant cohort were; median age 24 years (range 0-74 years), 48% male, 36% were homozygous and 37% were heterozygous for F508del, 24% had CFrelated diabetes (CFRD), 43% were taking CFTR modulator therapy, and median best FEV 1 prior to infection was 73% predicted, (range 18-123%) ( Table 1) . One of the seven deaths, in a non-transplant patient, was reported by the clinical team as being related to advanced cystic fibrosis, not SARS-CoV-2. In the non-transplant cohort, 4 deaths were recorded, 2 of which had a best FEV1 the year prior to infection of <40% predicted and 2 with 40-70% predicted.	./cache/cord-280062-1qrav1d5.txt	./txt/cord-280062-1qrav1d5.txt