id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-279518-z3k7zaw4	Xue, Xiaotong	High expression of ACE2 on the keratinocytes reveals skin as a potential target for SARS-CoV-2	2020-05-23		.txt	text/plain	1506	89	52	High ACE2 expression was identified in the type II alveolar cells (AT2), bronchial transient secretory cells, small intestinal epithelium cells and the oral epithelial cells in accordance with respiratory clinical manifestations and rare clinical manifestations such as gastrointestinal symptoms, suggesting the respiratory droplet, digestive ２ and fecal-oral transmission routes of SARS-CoV-2 (Lukassen et al., 2020; Liang et al., 2020; Xu et al., 2020a) . Therefore, we hypothesized that the expression and distribution of ACE2 in human organs and tissues could reflect the potential infection routes of SARS-CoV-2. However, scRNA-seq has not yet been applied to examine the ACE2 expression in the cells of skin tissues, and the transmission of this virus by percutaneous routes remains unclear. In conclusion, the high expression of ACE2 on keratinocytes in human skin indicated that percutaneous transmission might be a potential risk route for SARS-CoV-2 infection, especially in condition of skin barrier dysfunction.	./cache/cord-279518-z3k7zaw4.txt	./txt/cord-279518-z3k7zaw4.txt