id author title date pages extension mime words sentences flesch summary cache txt cord-278491-cnqxsno8 Wang, K. Longitudinal dynamics of the neutralizing antibody response to SARS-CoV-2 infection 2020-07-17 .txt text/plain 3139 216 57 Methods Blood samples (n=173) were collected from 30 COVID-19 patients over a 3-month period after symptom onset and analyzed for SARS-CoV-2-specific NAbs, using the lentiviral pseudotype assay, coincident with the levels of IgG and proinflammatory cytokines. 9, 10 However, the dynamics and roles of SARS-CoV-2specific NAbs and their correlation with antibody responses have not been explored in COVID-19 patients more than two months after symptom onset. Our study may provide useful information regarding dynamic changes in NAbs in COVID-19 patients during the acute and convalescent phases and aid in the development of vaccines against SARS-CoV-2. 15, 16 The short-term humoral immune response in COVID-19 patients is also highly consistent with that observed in patients infected with SARS-CoV and MERS-CoV, 17, 18 who show a rapid decrease in virus-specific antibody titers within 3-4 months. In summary, we determined the dynamics of NAb titers within 3 months after symptom onset in 30 SARS-CoV-2-infected patients and found a positive correlation between NAb titers and IgG antibodies. ./cache/cord-278491-cnqxsno8.txt ./txt/cord-278491-cnqxsno8.txt