id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-278271-rpq62xhl	Lyu, Jinglu	Reflection on lower rates of COVID-19 in children: does childhood immunizations offer unexpected protection?	2020-05-15		.txt	text/plain	4641	230	46	The frequent childhood vaccinations and repeated pathogens infections might be resulting in trained immunity of innate immune cells, immune fitness of adaptive immune cells or cross-protection of antibodies in the children. Candida isolated from 4 airway specimens in a case report of patients with new coronavirus pneumonia Compared with adult cases, children tend to have milder symptoms, shorter disease course and generally better prognosis. found that memory lymphocytes can also mediate longer-term cross-protection as a byproduct of adaptive immunity: CD8 + memory T cells can be activated by cytokines (IL-12 and IL-18) in early stages of infection in an antigen-independent manner, leading to the production of IFN-γ and enhanced response to subsequent infectious agents (45) . Equipping confirmed COVID-19 patients with these vaccinations as emergent prophylaxis may prevent severe illness caused by secondary infection, in the meantime, it may mobilize the host's lymphocyte response to the opposite direction in response to SARS-CoV-2.	./cache/cord-278271-rpq62xhl.txt	./txt/cord-278271-rpq62xhl.txt