id author title date pages extension mime words sentences flesch summary cache txt cord-277640-vy7ex5lv Calderaro, Adriana SARS-CoV-2 infection diagnosed only by cell culture isolation before the local outbreak in an Italian seven-week-old suckling baby 2020-05-14 .txt text/plain 1171 63 52 The virus isolate was named SARS-Cov-2/human/Parma/1/2020.Cell culture still remains the only reference diagnostic method also for emerging viruses, allowing to reveal cytopathogenic viruses and demonstrating their infectivity. To the best of our knowledge, no literature evidence of SARS-CoV-2 virus infection diagnosed including virus isolation is present for suckling babies and very little evidence for new-borns (Lu and Shi, 2020, Wang et al., 2020); in these reported cases, laboratory diagnosis was only done by molecular methods. The patient was referred to the Neonatology ward of the University Hospital of Parma (Italy) in the night of Only the culture isolation of this cytopathogenic agent allowed its final identification as SARS-CoV-2. To the best of our knowledge, in the international literature at the time of the manuscript submission, no other reports of infants of this age describing the laboratory diagnosis of SARS-CoV-2 infection including virus isolation together with RNA detection were present. ./cache/cord-277640-vy7ex5lv.txt ./txt/cord-277640-vy7ex5lv.txt