id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-277410-lt19mijb	Salvatore, Phillip P	Epidemiological Correlates of PCR Cycle Threshold Values in the Detection of SARS-CoV-2	2020-09-28		.txt	text/plain	3282	206	52	METHODS: Using testing data collected during a prospective household transmission investigation of outpatient and mild COVID-19 cases, we examined the relationship between Ct values of the viral RNA N1 target and demographic, clinical, and epidemiological characteristics collected through participant interviews and daily symptom diaries. Ct values were significantly lower among participants under 18 years of age (p=0.01) and those reporting upper respiratory symptoms at the time of sample collection (p=0.001) and were higher among participants reporting no symptoms (p=0.05). Given the paucity of data examining associations of these factors with Ct value at the time of diagnosis, we sought to identify relationships between Ct values and time since onset, demographic factors, and symptoms among laboratory-confirmed COVID-19 cases identified in a multistate investigation of SARS-CoV-2 household transmission. Cycle threshold (Ct) values for SARS-CoV-2 rRT-PCR target probes N1 and N2 are plotted against the time elapsed between symptom onset and NP specimen collection in panel 1A.	./cache/cord-277410-lt19mijb.txt	./txt/cord-277410-lt19mijb.txt