id author title date pages extension mime words sentences flesch summary cache txt cord-275894-puwaty70 Wajnberg, A. SARS-CoV-2 infection induces robust, neutralizing antibody responses that are stable for at least three months 2020-07-17 .txt text/plain 2493 190 61 Here we report that the vast majority of infected individuals with mild-to-moderate COVID-19 experience robust IgG antibody responses against the viral spike protein, based on a dataset of 19,860 individuals screened at Mount Sinai Health System in New York City. We also show that titers are stable for at least a period approximating three months, and that anti-spike binding titers significantly correlate with neutralization of authentic SARS-CoV-2. In order to determine if antibodies induced against the spike protein exert neutralizing activity, we 111 performed a well-established, quantitative microneutralization assay (18) based on authentic 112 SARS-CoV-2 with 120 samples of known ELISA titers ranging from 'negative' to 1:2880. . https://doi.org/10.1101/2020.07.14.20151126 doi: medRxiv preprint with authentic SARS-CoV-2 virus, and the vast majority of individuals with antibody titers of 1:320 167 or higher show neutralizing activity in their serum. ./cache/cord-275894-puwaty70.txt ./txt/cord-275894-puwaty70.txt