id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-275360-uphdzj5l	Sahajpal, Nikhil Shri	Proposal of Reverse Transcription-PCR–Based Mass Population Screening for SARS-CoV-2 (COVID-19)	2020-07-30		.txt	text/plain	1675	92	49	Herein, we propose a mass population screening approach, based on sample pooling strategy for rapid and wide-scale population screening that may be adopted by laboratories currently using RT-PCR based methods to test for SARS-CoV-2. The strategy we propose leverages on existing high throughput systems that employ high analytically sensitive [limit of detection (LOD) 5-20 copies/ml] real-time PCR chemistries, coupled with pooling of samples based on current COVID-19 incidence rates. 6 The advantages of this approach include the potential to catch up with huge testing deficits, reducing turnaround times and most importantly ensuring enormous savings through the most efficient use of RNA extraction and/or testing kits, which even today are in significant short supply. The strategy we propose leverages existing high throughput systems which employ analytically high sensitive RT-PCR chemistries, coupled with pooling of samples based on current COVID-19 incidence rates.	./cache/cord-275360-uphdzj5l.txt	./txt/cord-275360-uphdzj5l.txt