id author title date pages extension mime words sentences flesch summary cache txt cord-274680-6pui91uu Gao, Chun Proinflammatory cytokines are associated with prolonged viral RNA shedding in COVID-19 patients 2020-10-14 .txt text/plain 2206 151 52 5 Many studies have found that older patients have a higher risk of having a severe case and they have a higher death rate from COVID-19, which may be related to a weaker host immune response for antiviral defense and an uncontrolled proinflammatory cytokine storm. [10] [11] Therefore, this retrospective study aimed to analyze the clinical characteristics of COVID-19 patients who experienced prolonged viral shedding and to investigate the contributing risk factors. This is a comprehensive report of 112 COVID-19 patients investigating the distinct characteristics and risk factors for prolonged SARS-CoV-2 viral RNA shedding. In our study, we found that COVID-19 patients with prolonged viral shedding were older (p<0.001) and presented with a higher rate of hypertension (p<0.001). This study focused on investigating the risk factors for COVID-19 patients with prolonged viral shedding. In summary, in this study, we investigated the distinct dynamics of the inflammatory response in COVID-19 patients with prolonged viral RNA shedding. ./cache/cord-274680-6pui91uu.txt ./txt/cord-274680-6pui91uu.txt