id author title date pages extension mime words sentences flesch summary cache txt cord-274286-07arhrv9 Hosier, H. First case of placental infection with SARS-CoV-2 2020-05-05 .txt text/plain 3935 237 50 Conclusion: This case demonstrates, for the first time, SARS-CoV-2 invasion of the placenta, highlighting the potential for severe morbidity among pregnant women with Covid-19. Levels of anti-SARS-CoV-2 IgG and IgM antibodies in the case study patient were among the highest observed in 56 Covid-19 + patients admitted to Yale New Haven Hospital. This report describes a case of second-trimester Covid-19 associated with preeclampsia and SARS-CoV-2 infection of the placenta. Further studies of placenta from women with Covid-19 may help address whether this is a histological feature associated with placental SARS-CoV-2 infection. RNA was extracted from homogenized placenta, umbilical cord, fetal lungs, heart kidney tissues (27-160 mg; stored in formalin) and maternal oral, nasal, and rectal swabs, saliva, urine, plasma, and serum post-operatively and tested for the presence of SARS-CoV-2 and human RNase P using the US CDC qRT-PCR assay as described 7 . ./cache/cord-274286-07arhrv9.txt ./txt/cord-274286-07arhrv9.txt