id author title date pages extension mime words sentences flesch summary cache txt cord-272414-oo8kcuf3 Chiocchetti, Roberto ACE2 Expression in the Cat and the Tiger Gastrointestinal Tracts 2020-08-13 .txt text/plain 3005 161 52 Although the evidence of ACE2-IR in the feline GIT does not necessarily indicate the possibility of viral replication and SARS-CoV-2 spread with stool, the findings in the present study could serve as an anatomical basis for additional studies considering the risk of the SARS-CoV-2 fecal-oral transmission between cats/felids, and between cats/felids and humans. Since the necessary condition for the enteric multiplication of SARS-CoV-2 is represented by the expression of its election receptor on the host cells, the present study immunohistochemically investigated the localization of ACE2 in the GIT of feline domestic (cat) and wild (tiger) species. The present study described the expression of the ACE2 receptor in the stomach and intestine of the cat and tiger for the first time and highlighted the GIT as a potential site of SARS-CoV-2 replication. ./cache/cord-272414-oo8kcuf3.txt ./txt/cord-272414-oo8kcuf3.txt