id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-271751-46oo9xv5	Ingraham, Nicholas E.	Shining a light on the evidence for hydroxychloroquine in SARS-CoV-2	2020-04-28		.txt	text/plain	1112	77	51	Chloroquine and hydroxychloroquine seem effective in killing SARS-CoV in vitro [1, 3] . Recent reports show it also may be effective at killing SARS-CoV-2-infected cells in vitro [4] . To date, no pre-clinical studies have evaluated the efficacy of hydroxychloroquine in the current SARS-CoV-2 pandemic. A recent article published in Chinese found no benefit with chloroquine in a 1:1 randomized trial with 30 patients [6] . Until data from randomized controlled trials are available, we suggest caution utilizing hydroxychloroquine off label for patients with COVID-19. There are currently no evidence supporting hydroxychloroquine as prophylaxis, but unfortunately these data are being extrapolated to the indication potentially resulting in drug shortages for patients with rheumatic diseases who require this medication. Preliminary study of hydroxychloroquine sulfate in treating common coronavirus disease (COVID-19) patients in 2019 Hydroxychloroquine and azithromycin as a treatment of COVID-19: preliminary results of an open-label nonrandomized clinical trial	./cache/cord-271751-46oo9xv5.txt	./txt/cord-271751-46oo9xv5.txt