id author title date pages extension mime words sentences flesch summary cache txt cord-270951-6nq3jwgr Amerio, Paolo COVID‐19 and psoriasis: Should we fear for patients treated with biologics? 2020-05-05 .txt text/plain 2258 154 53 One of question is if psoriasis patients treated with immunomodulating and immunosuppressive drugs have to discontinue their treatment in the midst of fears for the infection and its consequences. Previous coronaviruses outbreaks reports, current published evidences on pathogenesis and on clinical reports of COVID infection in immunosuppressed patients are used to make a scientifically based decision. 3 Recently some concern over the possibility that cytokine directed immunosuppressive treatment may be a risk factor for SARS-CoV-2 infection in psoriasis patients has been expressed. Given the potential role of proinflammatory cytokines in the pathogenesis of SARS and MERS severe disease, also ant inflammatory drugs have been suggested as novel treatments in these diseases. High levels of IL-2, IL-7, GM-CSF, MIP1-α, and TNF-α have also been correlated with disease severity in SARS-CoV-2 infected patients. The use of anti-inflammatory drugs in the treatment of people with severe coronavirus disease 2019 (COVID-19): the perspectives of clinical immunologists from China ./cache/cord-270951-6nq3jwgr.txt ./txt/cord-270951-6nq3jwgr.txt