id author title date pages extension mime words sentences flesch summary cache txt cord-270743-yyl50z94 Haseli, Sara Reply to “MRI evaluation of the olfactory clefts in patients with SARS-CoV-2 infection revealed an unexpected mechanism for olfactory function loss” 2020-06-10 .txt text/plain 619 40 47 title: Reply to "MRI evaluation of the olfactory clefts in patients with SARS-CoV-2 infection revealed an unexpected mechanism for olfactory function loss" We read with great interest the letter by Eliezer and Hautefort discussing our recent report in Academic Radiology of magnetic resonance imaging (MRI) findings in a patient with coronavirus disease-2019 (Covid-19) and enumerating the possible mechanisms of SARS-CoV-2-induced anosmia 1 . In the apparent absence of anatomical changes on MRI and to assess a putative loss of neuronal function in anosmia of Covid-19, we performed 18 FDG PET/CT scan in a patient with isolated anosmia under neutral olfactory condition, which revealed hypoactivity of the left orbitofrontal cortex, thus suggesting a probable neuroinvasive mechanism for anosmia of Covid-19 8 . MRI evaluation of the olfactory clefts in patients with SARS-CoV-2 infection revealed an unexpected mechanism for olfactory function loss. Non-neural expression of SARS-CoV-2 entry genes in the olfactory epithelium suggests mechanisms underlying anosmia in COVID-19 patients. Non-neural expression of SARS-CoV-2 entry genes in the olfactory epithelium suggests mechanisms underlying anosmia in COVID-19 patients. ./cache/cord-270743-yyl50z94.txt ./txt/cord-270743-yyl50z94.txt