id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-270613-vnjuubt4	Poon, Terence C.W.	Proteomic analysis reveals platelet factor 4 and beta‐thromboglobulin as prognostic markers in severe acute respiratory syndrome	2012-06-28		.txt	text/plain	3358	176	49	The data on 20 SARS-associated proteomic features and ten serological variables (ALT, LDH, bilirubin, total protein, albumin, globulin, C-reactive peptide, total white blood cells, lymphocyte count, neutrophil count) from 38 SARS patients before treatment were subjected to forward stepwise multiple logistic regression (SPSS, v18, IBM) for prediction of the ICU admission and/or supplemental oxygen administration in the later period. Among the 20 SARS-associated proteomic features and ten serological variables (ALT, LDH, bilirubin, total protein, albumin, globulin, C-reactive peptide, total white blood cells, lymphocyte count, neutrophil count), multiple logistic regress analyses identified four proteomic features (m/z 6634, m/z 7769, m/z 8635, m/z 8865) as statistically significant prognostic markers for supplemental oxygen administration or ICU admission in the later period. To confirm the differential patterns and the identities of the m/z 7769 and m/z 8865 proteomic features, serum samples were subjected to Western blot analysis using specific antibodies against PF4 and beta-TG.	./cache/cord-270613-vnjuubt4.txt	./txt/cord-270613-vnjuubt4.txt