id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-270606-r46pbaf0	Rashed, Mohamed Z.	Rapid detection of SARS-CoV-2 antibodies using electrochemical impedance-based detector	2020-10-07		.txt	text/plain	3135	152	42	Here, we demonstrate rapid label-free electrochemical detection of SARS-CoV-2 antibodies using a commercially available impedance sensing platform. A 16-well plate containing sensing electrodes was pre-coated with receptor binding domain (RBD) of SARS-CoV-2 spike protein, and subsequently tested with samples of anti-SARS-CoV-2 monoclonal antibody CR3022 (0.1 [Formula: see text] g/ml, 1.0 [Formula: see text] g/ml, 10 [Formula: see text] g/ml). In this study, we report a non-faradic capacitive immunosensing assay using a commercially-available impedance detection system that uses specialized well-plates that have integrated sensing electrodes from ACEA Biosciences ( Figure 1 ). Coating the wells with anti-SARS-CoV-2 antibodies instead of spike RBD antigen may enable rapid EIS detection of viral particles in patient samples, although further testing is needed to determine the limit of detection for that approach. An alternative medical Rapid Detection of SARS-CoV-2 Antibodies Figure S1 : Measurements with greater time resolution were acquired with a different impedance analyzer (Agilent 4294A, 10 kHz, 0.5 V), demonstrating improved resolution.	./cache/cord-270606-r46pbaf0.txt	./txt/cord-270606-r46pbaf0.txt