id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-269383-1tyorrb0	Lai, Christopher K C	Prospective study comparing deep-throat saliva with other respiratory tract specimens in the diagnosis of novel coronavirus disease (COVID-19)	2020-08-01		.txt	text/plain	2845	186	57	METHODS: We performed a prospective study in two regional hospitals in Hong Kong RESULTS: We prospectively examined 563 serial samples collected during the virus shedding periods of 50 patients: 150 deep-throat saliva (DTS), 309 pooled-nasopharyngeal (NP) and throat swabs, and 104 sputum. International authorities recommend laboratory diagnosis of SARS-CoV-2 infection should base on real-time PCR (RT-PCR) detection of viral RNA in respiratory specimens [2, 3] . In another study by the same research group [23] , they tested archived nasopharyngeal swabs and posterior oropharyngeal saliva specimens from 58 confirmed COVID-19 patients using Xpert® Xpress SARS-CoV-2 assay. To date, our current study provides the largest number of patients with prospectively collected saliva specimens throughout the clinical course and with head-to-head comparison of DTS to both upper and lower tract respiratory samples. DTS contains lower viral RNA concentration and is less sensitive in detecting SARS-CoV-2 infection than sputum and pooled NP and throat swabs.	./cache/cord-269383-1tyorrb0.txt	./txt/cord-269383-1tyorrb0.txt