id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-269101-7altkx5u	Jakhmola Mani, Ruchi	Deciphering underlying mechanism of Sars-CoV-2 infection in humans and revealing the therapeutic potential of bioactive constituents from Nigella sativa to combat COVID19: in-silico study	2020-10-28		.txt	text/plain	4934	270	50	title: Deciphering underlying mechanism of Sars-CoV-2 infection in humans and revealing the therapeutic potential of bioactive constituents from Nigella sativa to combat COVID19: in-silico study An amazing herb, Nigella sativa, having antiviral, antihypertensive, antidiarrhoeal, analgesics, and anti-bacterial properties, needs to be explored for its efficacy against SARS-CoV-2, the causative agent of COVID-19. sativa bioactive constituents were similar to the pathways followed in SARS-COV-2 pathology, like renin-angiotensin system, kidney functions, regulation of blood circulation, blood vessel diameter, etc. To study the effectiveness of N.sativa against SARS-CoV-2, protein interactions studies were carried out for receptors predicted via swiss target prediction for this plant's bioactive constituents, to understand their beneficial effect on SARS-CoV-2 in humans. sativa bioactive constituents by protein interaction and docking studies as well as proven their binding efficiency with ACE2 receptor and now this can be studied further in wet lab and be formulated as the medicine to combat the deadly disease COVID-19.	./cache/cord-269101-7altkx5u.txt	./txt/cord-269101-7altkx5u.txt