id author title date pages extension mime words sentences flesch summary cache txt cord-268406-3v309r41 Grajewski, Rafael S. A missing link between SARS‐CoV‐2 and the eye?: ACE2 expression on the ocular surface 2020-06-12 .txt text/plain 668 53 53 We applaud Lange et al.1 for their extensive efforts to analyse entry factors for severe acute respiratory syndrome coronavirus (SARS-CoV-2) into conjunctival epithelial cells covering the ocular surface, which is an important albeit controversially discussed issue1,2 . A missing link between SARS-CoV-2 and the eye?: ACE2 expression on the ocular surface Before incubation with the primary antibody, tissue was subjected to heat-induced epitope retrieval using Target Retrieval Solution pH 9 (catalog #S2367; Dako). The location of ACE2 expression at the ocular surface enables direct contact of SARS-CoV-2 with conjunctival cells, raising the question how often this occurs and if protective mechanisms of tears and conjunctiva might prevent conjunctivitis to happen more frequently. 6 In summary, our results provide an important addition to the results of Lange et al 1 and other works by clearly demonstrating specific ACE2 expression in conjunctival epithelial cells, providing the receptor for direct entry of SARS-CoV-2. ./cache/cord-268406-3v309r41.txt ./txt/cord-268406-3v309r41.txt