id author title date pages extension mime words sentences flesch summary cache txt cord-266616-boeb1xcp Liu, Yu Regulatory T cells: A potential weapon to combat COVID‐19? 2020-08-06 .txt text/plain 4158 233 49 This review discusses the clinical and pathological features of COVID‐19, the roles of immune cells in pathological processes, and the possible avenues for induction of immunosuppressive T regulatory cells attenuating lung inflammation due to viral infection. 13, 19, 37, 38 In a mouse model study by Fulton et al, 38 evaluating the balance between virus clearance and immunopathology, Foxp3 + CD4 + regulatory T cells were shown to accumulate in mediastinal lymph nodes and the lungs of infected animals and to reduce immunopathology by regulating the responses of CD8 effector T cell during infection of respiratory syncytial virus. 38 IL-10 and TGF-β, antiinflammatory cytokines, could suppress the activity of NK cells, macrophage, cytotoxic CD8 T cells, and T helper cells 1 to reduce inflammatory storm caused by those during virus infection (Figure 1 ). Current pathology reports have revealed that the lung tissues in people infected with SARS-CoV-2 were prominently infiltrated with multinucleated giant cells and inflammatory cells. ./cache/cord-266616-boeb1xcp.txt ./txt/cord-266616-boeb1xcp.txt