id author title date pages extension mime words sentences flesch summary cache txt cord-266536-4frv2vb7 Martel, Jan Could nitric oxide help to prevent or treat COVID-19? 2020-05-06 .txt text/plain 2067 110 44 In view of the pandemic caused by the novel coronavirus (SARS-CoV-2), clinical trials have been designed to examine the effects of inhaled nitric oxide in COVID-19 subjects. In view of the pandemic caused by the novel coronavirus (SARS-CoV-2), clinical trials have been designed to examine the effects of inhaled nitric oxide in COVID-19 subjects. During the 2002-2003 severe acute respiratory syndrome (SARS) epidemic, also caused by a coronavirus, inhaled NO was tested in six SARS patients, producing beneficial effects that include decreased pulmonary hypertension, improved arterial oxygenation, and reduced spread and density of lung infiltrates [5] . In addition, limiting the lifestyle factors that reduce endogenous NO levels in the airways-such as mouth breathing and smoking-may also help to reduce SARS-CoV-2 viral load and symptoms of COVID-19 pneumonia by promoting more efficient antiviral defense mechanisms in the respiratory tract. ./cache/cord-266536-4frv2vb7.txt ./txt/cord-266536-4frv2vb7.txt