id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-266022-aco5kpaj	Matusiak, Magdalena	Expression of SARS-CoV-2 entry receptors in the respiratory tract of healthy individuals, smokers and asthmatics	2020-09-29		.txt	text/plain	1837	122	48	We analyzed publicly available RNA microarray datasets for SARS-CoV-2 entry receptors and cofactors ACE2, TMPRSS2, BSG (CD147) and FURIN. Furthermore, respiratory epithelia were negative for ACE-2 and TMPRSS2 protein expression while positive for BSG and furin, suggesting a possible alternative entry route for SARS-CoV-2. First, by plotting the first 2 principal components computed on ACE2, TMPRSS2, BSG and FURIN expression across smokers' and asthmatics' datasets, we verified that there were no detectable batch effects within each of the six microarray datasets we sought to analyze (Figs. We next examined four RNA microarray datasets for ACE2, TMPRSS2, BSG and FURIN expression in airway epithelia from patients with a common respiratory disease, asthma. Abbreviations SARS-CoV-2: Severe acute respiratory syndrome coronavirus 2; COVID-19: Coronavirus disease 2019; ACE-2: Angiotensin I converting enzyme 2; TMPRSS2: Transmembrane serine protease 2; BSG: Basigin; XIST: X inactive specific transcript; RPS4Y1: Ribosomal protein S4 Y-linked 1 SARS-CoV-2 Receptor ACE2 Is an Interferon-Stimulated Gene in Human Airway Epithelial Cells and Is Detected in Specific Cell Subsets across Tissues	./cache/cord-266022-aco5kpaj.txt	./txt/cord-266022-aco5kpaj.txt