id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-265473-ju81kiyw	Balmeh, Negar	Predicted therapeutic targets for COVID-19 disease by inhibiting SARS-CoV-2 and its related receptors	2020-08-07		.txt	text/plain	2854	160	49	Therefore, different approaches have investigated against disease development and infection in this research; First, We identified hsa-miR-1307-3p out of 1872 pooled microRNAs, as the best miRNA, with the highest affinity to SARS-CoV-2 genome and its related cell signaling pathways. Approximately 377 predicted and valid targets of hsa-miR-1307 which were predicted The best herbal compounds for ACE2, TMPRSS2, GRP78, and AT1R receptors were identified based on their binding energy. The molecular docking results of the ACE2, TMPRSS2, GRP78, and AT1R receptors with medicinal herbal compounds are presented in Supplementary Table 2 . Increased expression of hsa-miR-1307-3p may lead to a reduction in SARS-CoV-2 replication through binding to the 3'UTR site of the virus genome. It has been confirmed that endocytosis and exocytosis are associated with virus entry and spread, therefore, controlling these pathways by hsa-miR-1307-3p could be an effective strategy for SARS-CoV-2 infection.	./cache/cord-265473-ju81kiyw.txt	./txt/cord-265473-ju81kiyw.txt