id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-265278-wf5pbvvt	Fishman, Jay A.	Case 29-2020: A 66-Year-Old Man with Fever and Shortness of Breath after Liver Transplantation	2020-09-17		.txt	text/plain	5266	317	40	In transplant recipiAfter infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), viral replication ensues in the respiratory epithelium, followed by viremia and systemic spread to organs by means of the angiotensin-converting-enzyme 2 receptor. 22 Graft rejection and toxic effects from calcineurin inhibitors may be difficult to distinguish from The varied presentation of SARS-CoV-2 infection reflects diversity in host immune responses, notably in immunosuppressed transplant recipients. Although the use of antiinflammatory drugs (e.g., high-dose glucocorticoids or interleukin-6 receptor antagonists) in solid-organ transplant recipients may have the additional benefit of protecting against rejection among patients who are receiving tapering courses of the immunosuppressive agents, especially when calcineurin inhibitors are discontinued because of severe disease, their efficacy in the context of solidorgan transplantation warrants testing in clinical trials. Human kidney is a target for novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection	./cache/cord-265278-wf5pbvvt.txt	./txt/cord-265278-wf5pbvvt.txt