id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-263350-i02z0hgx	Nagata, Noriyo	Pathological and Virological Analyses of Severe Acute Respiratory Syndrome–Associated Coronavirus Infections in Experimantal Animals	2006		.txt	text/plain	982	56	52	To determine the pathological features of SARS-CoV infection in experimental animals, its clinical, pathological, and virological features were investigated in cynomolgus monkeys, BALB/c mice, and F344 rats. In monkeys, following intranasal inoculation with 10 6 TCID 50 of SARS-CoV, the virus was isolated from throat and nasal swabs, and the viral genome was detected in rectal swabs collected between 2 and 7 days postinoculation (p.i.). Angiotensin-converting enzyme 2 (ACE2, a receptor for SARS-CoV 2 antigen-positive cells were observed in the virus-infected area and were repairing swelled type II alveolar epithelium in the lung of monkeys ( Figure 1A , B, and C). In BALB/c mice, the virus was detected in nasal and lung washes on days 3 and 5 after intranasal inoculation with 10 6 TCID 50 of SARS-CoV. In these experimental animals, ACE2 antigen-positive cells were observed in the virus-infected area and were repairing swelled type II alveolar epithelium (Table 1 ).	./cache/cord-263350-i02z0hgx.txt	./txt/cord-263350-i02z0hgx.txt