id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-261435-wcn4bjnw	Ren, Xianwen	Large-scale single-cell analysis reveals critical immune characteristics of COVID-19 patients	2020-10-29		.txt	text/plain	8495	468	57	Notably, the percentages of megakaryocytes 207 and monocytes in PBMCs were elevated, particularly in severe COVID-19 patients during 208 the disease progression stage (Figure 2A) The increased plasma B cells in peripheral blood appeared to be derived from active 231 proliferation of plasmablasts and transitions from memory B cells based on the paired BCR 232 sequencing analyses. Similarly, the clonal expansion of 398 a central memory CD4+ T cell cluster highly expressing AQP3 (T_CD4_c02-AQP3) was 399 also associated with the triad interaction by disease severity, age, and sex ( SARS-CoV-2 detected in multiple epithelial and immune cell types with 414 interferon response phenotypes 415 The enrichment of plasma B and proliferative T cells in BALF and the elevation of these 416 cells in PBMCs of COVID-19 patients highlighted the roles of these cells in combating 417 SARS-CoV-2 infection.	./cache/cord-261435-wcn4bjnw.txt	./txt/cord-261435-wcn4bjnw.txt