id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-261405-n05wjimk	Lui, Grace	Viral dynamics of SARS-CoV-2 across a spectrum of disease severity in COVID-19	2020-04-18		.txt	text/plain	1157	81	56	reported in this journal that viral shedding of SARS-CoV-2 in nasal swabs was longer in intensive care unit (ICU) patients compared with non-ICU patients with Coronavirus Disease 2019 (COVID-19). 3 We collected serial upper (pooled nasopharyngeal and throat swabs, N=75) and lower respiratory tract samples (sputum and tracheal aspirate, N=43), peripheral blood plasma (N=50), urine (N=43) and stool (N=43) samples from all participants, and monitored SARS-CoV-2 viral loads in these samples. In all five participants with severe/critical and three with moderate disease, viral loads in respiratory tract samples continued to rise and peaked in the second week of illness (range 5.57-9.66 log copies/mL). In this study of patients with COVID-19 across a wide spectrum of severity, we observed that viral shedding in the respiratory tract lasting longer than 14 days was common. In more severe disease, viral load appeared to peak in the second week of illness in both upper and lower respiratory tract.	./cache/cord-261405-n05wjimk.txt	./txt/cord-261405-n05wjimk.txt