id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-261307-qmh3wtqo	Evans, Scott E.	Inducible Epithelial Resistance against Coronavirus Pneumonia in Mice	2020-10-17		.txt	text/plain	658	38	44	, a single PUL-042 treatment significantly improved survival of otherwise lethal SARS-CoV infection and significantly reduced the lung MERS-CoV burden 3 days after challenge, congruent with our prior work demonstrating a consistent correlation between survival advantage and reduced pathogen burden. Although it is suspected that a second pandemic wave may arise concurrently with seasonal influenza, a patient with a virus-like illness can be preemptively treated with PUL-042 with the expectation that she or he will appreciate a benefit, whether the syndrome results from SARS-CoV-2, influenza A, both viruses, or another pathogen. The emergence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) represents the latest threat to global health security, and the pressure to identify effective therapeutics during this pandemic is immense. After an early report of a "cytokine storm" in patients with coronavirus disease (COVID-19) , there is increased interest in anti-IL-6 therapy as a treatment option, with ill-defined criteria for use (1). Inducible epithelial resistance against acute Sendai virus infection prevents chronic asthma-like lung disease in mice	./cache/cord-261307-qmh3wtqo.txt	./txt/cord-261307-qmh3wtqo.txt