id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-260624-rqjeacow	Gu, Jiang	Multiple organ infection and the pathogenesis of SARS	2005-08-01		.txt	text/plain	5320	271	51	SARS viral particles and genomic sequence were detected in a large number of circulating lymphocytes, monocytes, and lymphoid tissues, as well as in the epithelial cells of the respiratory tract, the mucosa of the intestine, the epithelium of the renal distal tubules, the neurons of the brain, and macrophages in different organs. In situ hybridization demonstrated SARS viral sequences in the cytoplasm of a large number of intact and degenerating epithelial cells of the lungs as well as in the scanty infiltrating lymphocytes and clustered macrophages ( Fig. 1, C and D) . (C) In situ hybridization of SARS genomic sequence of the lung from a SARS victim who died 62 d after the onset of high fever detected a large number of pulmonary epithelial cells (small arrows) that contained the virus. In the autopsy samples, in situ hybridization and EM demonstrated virus-infected immune cells in the circulating blood, spleen, lymph nodes, and lymphoid tissue of various organs.	./cache/cord-260624-rqjeacow.txt	./txt/cord-260624-rqjeacow.txt