id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-257792-m7nij17v	Ng, Oi-Wing	Memory T cell responses targeting the SARS coronavirus persist up to 11 years post-infection	2016-04-12		.txt	text/plain	4237	203	56	In this study, the screening for the presence of SARS-specific T cells in a cohort of three SARS-recovered individuals at 9 and 11 years post-infection was carried out, and all memory T cell responses detected target the SARS-CoV structural proteins. As shown in Fig. 1 , higher frequencies of IFN␥producing SFUs were observed for in vitro-expanded PBMCs from SARS subject 1 compared to the healthy individual, suggesting the presence of SARS-specific memory T cells at 9 years post-infection. In another study looking at SARSspecific memory T cell responses in SARS-recovered individuals at 4 years post-infection, 28.75% of them presented T cell responses to M peptides [22] , further supporting the role of M protein in eliciting dominant cellular immunity during SARS-CoV infection. In SARS subject 1 at 6 years post-infection, a HLA-B*1525-restricted memory CD8 + T cell response targeting the N53 peptide, corresponding to residues 261-275 of N protein, was detected.	./cache/cord-257792-m7nij17v.txt	./txt/cord-257792-m7nij17v.txt