id author title date pages extension mime words sentences flesch summary cache txt cord-257751-n7w1psr4 Halperin, Daniel T. Coping With COVID-19: Learning From Past Pandemics to Avoid Pitfalls and Panic 2020-06-30 .txt text/plain 6378 386 57 As we wrestle with how best to mitigate COVID-19, it is imperative to concur on the likely main drivers of transmission (notably, infection clusters resulting from prolonged indoor respiratory exposure) in order to clearly explain risk and to determine the most effective, realistic behavioral and other means to reduce illness and mortality. What is clear, based on evidence from several countries (and despite media attention to statistically anomalous cases of healthy and younger victims), is that severe outcomes and deaths from COVID-19 are overwhelmingly associated with preexisting (and especially multiple) serious illnesses such as diabetes and heart disease, [14] [15] [16] more so in men and particularly when exacerbated by obesity and smoking. Moreover, the fact that between 96% (in the United States 16 ) and more than 99% (in Italy 14 ) of COVID-19-related deaths, at any age, have occurred in persons with preexisting conditions could suggest that even very old but otherwise healthy people may not be at greatly elevated risk of dying from the disease. ./cache/cord-257751-n7w1psr4.txt ./txt/cord-257751-n7w1psr4.txt