id	author	title	date	pages	extension	mime	words	sentences	flesch	summary	cache	txt
cord-257403-jujrazsr	Yin, Changchuan	Genotyping coronavirus SARS-CoV-2: Methods and implications	2020-04-27		.txt	text/plain	2614	179	53	Abstract The emerging global infectious COVID-19 disease by novel Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) presents critical threats to global public health and the economy since it was identified in late December 2019 in China. In this study, we use the Jaccard distance of the SNP mutations of SARS-CoV-2 genomes to measure the dissimilarity of virus isolates. From the SNP profiles of SARS-CoV-2 strain, high-frequency mutations predominate in the virus isolations, therefore, these high-frequency mutations probably contribute to increased transmissibility. This study employs the substitutions variants in genotyping for understanding the evolution and transmission of SARS-CoV-2, however, structural variants including insertions, deletions, and copy number variation are critical for virus pathogenicity [40] and human pathology [41, 42] . In this study, the complete genomes of SARS-CoV-2 are used for SNP genotype calling. Comparative full-length genome sequence analysis of 14 SARS coronavirus isolates and common mutations associated with putative origins of infection	./cache/cord-257403-jujrazsr.txt	./txt/cord-257403-jujrazsr.txt